You could read through the Patch Notes:

https://forums.larian.com/ubbthreads.php?ubb=showflat&Number=834832#Post834832

Mostly no, except the three NPC Fishermen near the buried Illithid in the beginning have been removed. Mostly no other changes except paladin, the Oathbreaker System (which adds an NPC) and Level 5.

Blackheifer