This isn't exactly new since we've largely been aware of the party composition since the first release. Now we have confirmation and our choices for companions and origin characters seems pretty grim.
Laezel is Lawful Stupid. It's hard to take her since she's a one note fanatic who will hurt herself in order to hurt other people. As an evil run you could play as her but otherwise it's hard to take her in your party.
Shadowheart is Chaotic Stupid. She's so obsessed with lying and betrayal its hard to play as or with her.
Astarion is Chaotic Stupid. You might want to play as him in an evil run, but he's otherwise hard to include.
Minthara is Lawful Evil. You can't play as her and it makes little sense to take her along even on an evil run because there's no way your goals align.
Gale is Lawful Jerk. You can argue from a good standpoint youre morally obligated to take him along but from an actually enjoying the game perspective he's hard to take.
I'll be generous and assume Karlach isn't going to be a poisoned chalice. That leaves making a party out of Karlach, Wyll, Jaheira, Minsc and Halsin with Gale as a sort of option if you're playing a good party and 4 picks to make out of those 6. 3 of them don't look to be available till midgame, only 3 of them are origin characters. As someone who prefers playing as female characters and spellcasters I'm feeling almost locked out of playing an origin character at all.
This is the way the game is going to be now but I wish in future Larian would either focus on having more companions or if they're focussing on having a smaller number of higher quality ones not making a large number of those intolerable one way or another.