Originally Posted by neprostoman
But I doubt that other players will be fine with playing standard DnD characters while one particular person goes for an unhinged homebrew like this. They'll most likely either humble this person to play something standard or request the DM to lift limitations for them as well and become the party of gifted, altered and diseased. Which can off-set the whole balance of the campaign and will not likely be permitted.

Something like this would definitely happen if someone ever allowed something like this laugh
Whenever a restriction appears somewhere, someone starts shouting that they are the exception to the rule that this restriction does not apply to.

Sometimes it's not a debate about whether it's technically possible, but rather a debate about whether it's extremely unnatural and doesn't spoil the immersion.
It reminds me of a video.