If you are trying to strictly rush the main story with zero side quests, no exploration, etc. it will take ~80 hours per playthrough, completionist single playthrough should be over 150 hours. But the game has a vast amount of choice and consequences and permutations, all kinds of endings, etc. All in all 175 hours worth of cutscenes to account for a huge number of player choices. If you want to see even half of that you'll need dozens of playthroughs. So this game will provide thousands of hours worth of content.
So do we think it's 50% more content than the entirety of DOS2 or twice the content then? For a single playthrough as a completionist that is.
I'm basing this on the fact that I have 220 hours in DOS2 and have played it twice, completionists both ways.