Gina got cancelled for making transphobic/homophobic comments and comparing being a conservative to Jews murdered during the holocaust.
Who cares?
She is an actress, not a politician...
I'll not comment on Gina Carano specifically as while I did read some stuff about it at the time Disney distanced themselves from her, I don't recall the details.
But speaking generally, I think the problem with employing actors who have publicly made statements that attack certain groups of people, using specifically LGBT folk as an example, is threefold.
EDIT: And as it's off at a tangent given this thread was about Karlach's face not her voice, I'll also pop it in spoiler tags ...
(1) Companies will have their own values, which in many cases will include a commitment to supporting and serving LGBT employees and customers. That wouldn't and shouldn't prevent them employing people of different views within reason, but if someone has been publicly vocal about attitudes that are antithetical to a company's values, then it makes it hard for that company to employ them without accusations of hypocrisy or failure to stand up for what they believe in.
(2) Companies have a duty of care to their employees. I personally would be very uneasy about asking an LGBT employee (of whom I'm sure Larian has a number given their size) to work with someone who had been vocal about their anti-LGBT attitudes and had advocated for measures that were likely to harm them and people like them.
(3) Again within reason I think people are generally able to separate art from the artist. But if an artist publicly and repeatedly expresses views, and attacks something that people experience as central to themselves such as sexuality or gender identity, that can get to be too big an ask. There are certainly a few creatives whose work I previously enjoyed that I no longer can because the first thing I think of now is the objectionable things they have said or done. And I think it would be unfair to LGBT gamers to include a prominent character in the game with a voice that it would be perfectly understandable if it kept reminding them of the hatred they experience from some quarters.
Put more succinctly, no-one forces actors to publicly express anti-LGBT views: it is their choice to go on record. And it seems good practice for everyone, not just actors, that if you wish to continue to be employed, don't publicly attack a section of your potential co-workers and the customer base for the products you're likely to be creating.
Anyway, that's all I'm going to say on that particular topic. Obviously folk are welcome to agree or disagree with any of the points I have made (as long as they do so calmly and without insulting anyone), but as it's a digression from the main topic of the thread and a discussion I don't want to prolong given it naturally touches on sensitivities, I won't respond publicly any further unless someone forces me to as a moderator.
If anyone wants to ask me anything specific about the above, feel free to PM me.