I would love it if the game kept track of how many times you've used the tadpole, how many tadpoles you've consumed from others, etc. And at the end of the game during the Final Fight you'd get a ST that is more difficult based on this tracker, possibly being impossible. If you fail, you turn into a mind flayer, lose all your sense of self, and join the Mind-Flayer Collective. Game End screen.

That'd be such a ballsy move from Larian. "You took the shortcut to gaining power, giving up parts of yourself and letting a stronger power gain control over you bit by bit. You took a risk and lost. Them's the breaks."