I mean, the fact that the tadpole has a whole progression system attatched to it is another bit of evidence that the anti-tadpole path is gonna have less content.
We don't know that. Possibly, you get locked into a number of endings at some point. Using the tadpole could exclude content as well. Both the endgame and various quests. Even endings to companions' storylines, if they leave early enough because of your actions.