I'll probably never stray from Gale being a Wizard. He is just so... Wizardish. Honestly, I probably will never spec out of OC's starting classes. Multi, sure, but not go out. The characters make sense in the class they have.
The only exception to this is, perhaps Shadowheart. If she switches patron deity, I might go for a different domain, too, but that's an RP thing mostly; just so she feels different after such a transformation.
