Gale's sudden but inevitable betrayal is to be expected. The others can be coopted to work together for mutual benefit. Siding with Minthara and the Goblins seems shortsighted as they turn on you even if you support them. Not to mention killing refugees is a waste of time and effort. What precisely will I gain from it? The slaves of the Absolute have better loot.
I definitely wouldn't trust him but we will probably be able to turn his plans against him. This is a game that is all about all of the skill checks and there are a lot methods like persuasion, deception, maybe mind control with the tadpole, etc. I fully plan to go through his story and if I can betray him and get him killed at the very end to avenge Mystra that would just be the best.