To be blunt, I don't min/max in PnP and I won't min/max in BG 3. If the game becomes too difficult to progress without min/maxing, I'll most likely just quit or get a mod that addresses the issue. Lowering difficulty is only an option with a mod that removes certain features, such as the general bonus to proficiency we get in story mode. However, I hope the game isn't balanced around min/maxing as that would probably cause issues.
I like playing unoptimized character and groups, they are far more interesting than optimized ones. If I fail a roll in BG 3, I very rarely reload but generally play along with outcome.
The main issue with min/maxers in BG3 is when you have one in a multiplayer session. But as long as one plays multiplayer with known people that shouldn't be an issue.