No. You're implying that you're missing something, but you're not. Not doing something has a result, just as much as doing something. Things just play out differently.
The Auntie Ethel scenario can play out in a *lot* of ways, depending on your class, where and when you encounter her first and more. By doing things a certain way, you 'miss out' on all the other ways. By not talking to her in town, you get a different encounter when you meet her. There's no need for some handholding-prompt. Just go and explore as you will and take things as they come. What's too important will always be on your path.
