As far as D:OS2 - check key bindings. If I rember it well there is a button that will allow you to aim AoEs freely.

There is not such exact problem in BG3. It has its own quirks.

What Rag referred to are two spells that target specific targets (bless and bane withoutnup asting target up to 3 targets of your choosing) but for some unknown reason we have to aim using AOE, with the game choosing targets for us, within this AOE. We have an indication whom the game is targeting, so it’s a matter of spending time wiggling the AOE around, until the game targets units it wants you to target.