I loved DOS2's combat but really couldn't get into the story which is why I stopped playing after around 90 hours... compare this to the 330+ hours I have in BG3 EA lol.
This said, I am not opposed to a new DoS, especially if it will carry on what they learned with BG3 when it comes to presentation and storytelling.
People say they'd want to see Larian tackle Planescape but honestly.... I just want them to do justice to the World of Darkness! I'd love to see them do Dark Ages. It doesn't even have to be Vampire the Masquerade/Requiem nor anything similar to a Bloodlines 2 (we all know how bad the paradox game is going to be lol) it could be changeling, werewolf the apocalypse, promethean.... damn, there is so much good lore that never gets used properly :(((