My own thought is that Baldur's Gate has sold decently well and could end up selling very well indeed. According to Larian, the number of people who owned a game tagged CRPG on Steam has risen from 13 million to 16 million in the last year and as the number-one selling CRPG on the platform, BG3 has doubtless driven much of that growth.

As for what it means for future D&D-related projects, I don't know but I do have some ideas. One thing I am positive of is that WoTC would not have given Larian the Baldur's Gate license without some discussion of future additions or expansions. Baldur's Gate is WoTC's biggest IP in the CRPG space and the idea that they would license it out with the idea it would be used for this one game and then nothing sounds ludicrous. I also think that WoTC has held on to control of when and how to announce any such expansions.

My own guess is that anything in that agreement is at least partially going to be tied to sales performance and that it will range from no further work at all if sales are below a certain threshold, to Larian having the option, through Larian either being required to do some form of add-on, expansion, or sequel--or failing that license the engine to someone else who would do such a project. I just checked the community hub and Baldur's Gate 1 has 845 in game--as opposed to Pillars of Eternity which has 372--that's not bad for a 25-year-old game.

So I'm sure we will be getting something soon enough. I'm just not sure what or how it's going to be released.