I'm probably going to alternate between 2 characters. If I end up liking one playthrough more than the other I may focus on that one and leave the second for later, but considering how familiar act 1 is going to be (no matter the 30% or so of things that will be different, it's still going to be act 1 lol) I think I'll get at least at the end of that before I decide which one to carry on.
