Originally Posted by rodeolifant
Minsc is a Ranger, but Barbarian fits his 'canon' too, what with him a Rashemi Berserker. Champion Fighter too, with the Fuuulll Plate, and Packing Steel.
Shadowheart is a Cleric of Shar, Rogue levels fit her too, what with her being a secret operative that steals stuff.
Wyll is a Warlock, but can pick Pally levels, I think. IT fits him, or at least, it did.
Jaheira is a Fighter/Druid, however you do that. It's not my 5E combination of the week, but we'll see. Action surge rocks for everyone.
MInthara is a Pally, but I can easily see her as an Eldritch KNight or something. Not much else. [War] Cleric, but then you'd have to pick a deity and unless the Absolute becomes available later, that makes no sense.
Halsin is a Druid. But, Maybe dip him in Totem-of-the-Bear Barbie or something. I think that fits him.
Astarion could be a lot of things, really. Rogue is fine, but I think Necromancer suits him, but Dex Fighter too.
Karlach, nah full on Barbie for her. Two levels of Fighter maybe.
Laezal- Full on Eldritch Knight. But. Maaybe Paladin. Yeah,. I see that, but the oath depends on her story.
Gale is a Wizzard, but which one? I think... ALteration. Could have Lore Bard dips.

Wait, hang on Is Gale really the only Arcane Caster in the whole list? I'm gonna find Tiax.
Shadowheart starts as too devoted to her faith to really justify my multiclassing IMO as she takes her mission for Shar very seriously and would likely only delve deeper in her faith. Now I suspect that redeeming her from the influence of shar might lead to a forced respec into a different cleric subclass but we don't really know.
Wyll is bound to serving a fiend...binding to a Paladin oath would be like getting stuck between a rock and a hard place...do good and keep oath but get punished by the fiend or obey the fiend but be branded an oathbreaker...bad match imo.
Jaheira we know next no nothing about.
Minthara I suspect her paladin background could become important in her story...she seems to be a fallen paladin of some description but we'll have to find out more.
Halsin - the only place I'll dip him is in a grave at the start of every playthrough...but seems basically all druid.
Astarion as a vampire depends on blood to live so being a master of stealth is kind of vital to him.
Karlach yeah, all barbarian for sure.
Lae'zel is rather ruthless and more evil aligned...she could not hold a paladin oath and would almost certainly end up oathbreaker.
Gale - he was one of the most powerful archmages alive, rommanced and betrayed the goddess of magic, but his ambition is still to be the most powerful mage. He would not multiclass into anything else.