A thousand times no. I've been saying for a long time that it's possible to have RPG species in way that is not racist but "sub races" of humans is a bit too closes to the racist fantasy for me.
What you would need to do to do it in way that is not racist would be implement a system like the one the Aetalis setting has that divides race and culture.
In Aetalis a human raised in a dwarven community would have the dwarven armor proficiencies etc.
Just keep the conversation tags related to region but let humans just be humans.
This doesn't mean we can't have the PHB variant human but - Mystra save me - no, no, no to human sub races.
