Well I'm probably not playing all the origin stories but I am definitely playing some of them. My first playthrough will be Dark Urge for sure. Beyond that I think at some point I will play as Astarion and possibly Gale but that's about it in terms of origins I want to play as.

I love Shadowheart, so she'll almost always be in my parties and across the many plythroughs I'm sure I'll romance her more than once but I don't want to play as her. Lae'zel will be in my parties quite often bud don't think I'll romance her a lot, maybe once. As for Karlach and Wyll, I don't much care for, so I suspect they'll get killed or sacrificed early in my playthroughs.