Plus if you ever roll a 1 you fail automatically and a 20 automatically succedes.
We haven't yet seen any rolls that require higher than 20 in the public footage of BG3 so far and don't think any were present in early access but they do exist in D&D and generally speaking if a success requires higher than 20 you still have to meet that value even if you roll a nat 20, so rolling nat 20 and failing a roll is possible in D&D when attempting particularly difficult challenges. I wonder if Larian have implemented this in the game...maybe they didn't but it could be something that comes up later in the game where you might start finding roll difficulties of 25 or even 30 if they want to be like "ok, you can try, good luck with that though".