If Astarion accidentally falls on a wooden stake, it's perma death yep.
“Accidentally”
Astarion: "Hey Tav, throw me a steak will you?"
Tav *throws stake*
Astarion: Do you have any idea of what’s at stake here?
Tav: Yes, you.
*Sticks a fence post in a cow, lights it on fire*
Now THAT'S a wood-in-steak!
...I'll see myself out.