Originally Posted by SaurianDruid
So far my 8 Charisma druid has succeeded on something like 80% of his Charisma checks through a combination of Guidance, Enhance Skill, and careful use of Inspiration Points. The times he did fail didn't end in brutal combat or life-and-death situations because I've been selective about where and to what end I use the charisma options to try and get a better outcome. I'm about 30 hours in right now.

Guidance is honestly so good. It automatically compensates for your deficit -1 no matter what and can be the equivalent of a +3 in CHA if you get a max roll.
Yeah if you're selective to try to avoid the tough rolls and with some bonuses you can kind of make do. But there are critical instances in the game where charisma and/or wisdom are absolutely critical. Depending on your choices there ARE forced 25 or 30 DC rolls that you must pass or lose a companion on the spot where the only alternative is giving in to their demands. So low charisma will force to either go down certain paths or lose companions.