I'm also experiencing reproducible crashing since Hotfix 3. I cannot load most save games made after Hotfix 3. Trying to load a save game crashes to desktop. I can load save games from Hotfix 2.1 or earlier.
It's obviously rubbish for you that the game is repeatedly crashing, but perhaps positive for getting a fix that you're finding the crash reproducible. Can I just check whether you've submitted your savegame and details of your setup to Larian via the Report a Bug link at the top of the launcher? That might help them diagnose and resolve the problem.
Yes, I submitted a ticket yesterday. I updated it today by responding to the email I received from their system. In that response I added additional information about troubleshooting I've done as well as attached an example save file - one that crashes both my PC and my Steam Deck.
Also, one issue with the "Report a Bug" link is that it limits attachments to 20 MB. My most recent save file (which reproducibly causes a crash) is 27 MB. Hopefully attaching it to my email reply allows them to view it as the 20 MB limit obviously means I could not submit it as part of the initial ticket.
