I'm about to throw away my first playthrough of about 30 hours after finding out about Karlach's "fate" and will NEVER have a playthrough where I recruit her. Finding out her fate has left me sad and angry.
And only the ones that leave you with a sour taste in you mouth and a knot in your stomach. Game just went from a solid 10/10 to a 3/10 for me because of this. In fact I'm so bummed out right now I don't even want to play the game anymore. Games should be fun to play. This just depressed me to no end.
I feel the same. I'm still slowly playing the game, hoping for an update. But honestly, I may start over and opt to never get Karlach in my party. I'll just make sure I never stumble past where she's located. She's in my party now and I was looking forward to her quests, but now that I know her ending, I don't think I can bear to watch it. So, even though I'm nearly done with Act 1, I think I should start over.