I did the 'no power' playthrough because I believed that there would be sizable consequences to the story if you did use them, ( I have also sort of heard this is not the case, which is disappointing, so I just pretend like that is the case and still don't use them). I played a warlock and you can also by-pass the first power exposure with a skill check there as a warlock too, but I think I remember in EA when you meet those three people in Act I, with the character that ends up dying, the situation was very different after you clicked on the dead body than it is now. Even having approval rating effects with the other companions and you could
crush the tadpole that comes out of them
or something. (not sure if I need a spoiler tag for that but I'll just put one anyway.)
Anyway, I don't remember exactly how it went as I stopped playing EA about a year ago, but I do remember that it felt better to me somehow than what we have now. And the tadpoles did feel like there were more stakes, less incentive to use them than currently, at least to me. Personally, even though the stakes seem to be gone, I wouldn't use them so my character doesn't use them, but I wish there was more of an in-game reason for me making that choice. It feels weird the 'power but no consequence thing.