Thanks for the heads up Cirrus550. I'm hoping that a reinstall to another drive, and deleting those folders will help. I'm still holding out for a fix from Larian or some sort of information, but it's disheartening not hearing much of anything even though this sounds like a fairly widespread problem.
Now assuming it is local setting, cache etc corruption (fixed by full clean install) Larian can not fix it any way. Only thing they can fix is prevent it happening in future.
