As much as I would love it, there is so much dialogue in BG/1 that I don't know if they could be fully voice actored with 90% of content cut? especially when you couldn't get the same voice actors so that'd change so much. Imagine Irenicus without Warner? I can't.
As for rule changes AD&D was streamlined, 5e was about returning to that simplificaitons of AD&D after the complications of 3.5, so the 'dumbed down' card doesn't really play here.
A remake, reimagination of BG1/2 in BG3s engine would be amazing, and I think it could work to be not fully voiced. It'd be a big investment though and probably draining as there wouldnt be allow of room for creativity, but if it took a new perspective, risk and interpretation (which i think would be better creatively and gameplay consideration) it'd be review bombed into nonexistence by nostalgia loyalists?
It just seems too volatile/risky ?
BG4 or BG3 stand alone campaign expansions that explore new stories would be my preference for follow up.