I had an amusing experience earlier.
Just started a new "no reload" sort of ironman game after Patch 1 came out. I failed to talk Gimblebock and crew from leaving, so I had to fight them. I got to the door that Andorn was guarding and failed to persuade him that Gimblebock had triggered a trap and needed help.
So I had to try lockpicking the door. I had six sets of lockpicks. And I was using Astarion along with Guidance.
I failed all six rolls. All I could do was shrug my shoulders and head for the grove.
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I just don't have enough data to know if the rng is off. There are times where it feels like it, but I know I probably have some anecdotal bias. I do hope someone manages to figure out a way to export some rolls so a real analysis can be done.