Currently in ACT 2, trying to talk to prisoners in Moonrise Towers. I get maybe half a line in before a Guard comes in and forcibly ends the conversation. Is it realistic? Sure, but it's also frustrating. I'm someone who enjoys listening to the voice acting and using the dialogue systems. I would rather break just a little realism for the sake of storytelling. Stop the world around us while we're talking or something. Make the Guard approach us AFTER the conversation.
It's just a frustrating waste otherwise.