First thing to understand is the constant crashes are happening to ALL players not just those who have modded the game. I didn't even play yesterday (patch day) and can't play at this point, no mods ever installed. I've even done a complete wipe including registry entries and re-install and crash crash crash.
Do not assume that a crashing game is caused by mods, sometimes this is the case but not Always. This time it is NOT mods. Un-modded people are crashing just a bad as modded players. Larian broke their game with patch 2. I just hope they fix it today or all the great reviews they've been getting are going to be getting less great. A weekend with a broken FOTM game will hurt them on the reviews. It needs to be fixed ASAP before the weekenders start playing tonight/tomorrow. The forums are already having issues with certain threads related to this issue as it is.