Okay I installed Patch 2. I haven't needed Mod Fixer since Pack 1 (actually forgot about that until tonight).

Tried to start game and got an error from Native Camera Tweaks about a dll. Grabbed the Native folder from BG3\bin and plonked it on my desktop.

Tried again and the game loaded. Then the save loaded and there I am in the Last Light inn (moved around a bit in there). Not touched any other mod.

Uninstalled and updated a few of my mods (including ImprovedUI). Game loaded.

Updated Native Camera Teaks and dumped the folder back into \bin.

Save loaded into the game without any errors or problems.

ImprovedUI no longer sits in the Override section, it's now in the left hand pane with the other mods.

The graphics in my game improved quite noticeably with Patch 1 and they seem to have improved but not quite as much with this patch (I'm not complaining). That's first impressions base on the interior of the LL inn. Larian said somewhere that they would tweak colours so that the colour you chose in CC was matched by what you saw in game. This doesn't seemed to have been addressed yet as my PC's face still looks like it is leather rather than the Mediterranean tan it was in CC. A minor niggle I can live with.

I'm none the wiser as to what is causing the problems for other people as I've not had any with either patch. I run the game directly from the BG3_DX11 exe (desktop shortcut as I do with any game).

Tomorrow I might even try playing the game again.