Last mini boss, act 2 tower, half orc lady(vague on purpose), i had a hard time with. On balanced I couldn't do it. Soon as that paladin came out, dead. Between smites and grits, plus high initiative, I just get wrecked.
Yeah, that fight is annoying as hell. I manadged on my second try on balanced mode, but that was mostly owed to me getting initiative than anything else. Well, and getting lucky with the saving throws both mine and the ones made by enemies.
But the first time ... was horrible.