Any decent person is already playing to make Lae'zel defy her god-queen, so I'm not sure why you think ingesting tadpoles is a sacrilege. Do people not understand that you can influence your friends and change their outlook on things in this game? It's like so many of you are just proving Larian's point over and over, that gamers will just blindly do whatever they think will get them the most approval points instead of thinking critically about the relationship between two people. As it stands right now, there is no reason not to persuade Lae'zel to take the tadpoles, because Larian chickened out and didn't implement any consequences.
I thought that, if I'll deny Lae'zel the zaith'isk, she would just murder me on the spot, and it will be game over. Now she has penalties on INT and WIS...
I thought that was a possibility too. But it was still the right thing. Mostly this game is about having fun, but Larian is very clearly trying to make a point about how gamers try to metagame every decision instead of just roleplaying and doing what their character believes is right. Stop trying to engineer optimal outcomes, stop trying to give everyone what you think they want, just do what your character thinks is right. And with all the ominous warnings about that machine, your character has every reason to believe Lae'zel shouldn't get into it.
The vague warnings are there but you have no idea what the consequences are plus the 30 DC is not exactly easy to make.
If you don't want to try and pass a 30 DC check then don't put anyone in the machine!
With the other cures I think I'm correct in saying that only the PC can partake. Why is the gith one different?
Because getting to the zaithisk is Lae'zel's primary motivation throughout the first act. Like...what kind of a question is this?
Has it really been so long since games had meaningful choice and consequence mechanics that people just plain forgot about the idea of actions having consequences?