I wondered whether Minsc might become a really valid tank, as he gets so many Resistances, with the mace from Shadowheart's quest giving him 18 strength and the gauntlets giving 18 agility you can focus on constitution completely. Add that +2 con heavy armour and the grymforge helmet as well as a shield and he will be quite formidable without the need of buffs in need to be retained on him. But in the end this holds true for all characters I suppose.