The base story is a "good" DM plot line. The various sub plots, some are very well done and others feel a bit forced. The various character relationships feel forced early on. Up until Act 3 the storyline progresses pretty well however in Act 3 things begin to feel forced and rushed.

I think my personal biggest gripe is the way the Tadpole storyline and game mechanics are tied together. There is no real reason to not use the Tadpole. There is no penalty for letting it dig deeper in your head and no reward for fighting it. This to me is a MAJOR part of the storyline, especially as your introduced to the game and is just basically cast aside by the end of the 1st Act.