I might draw the ire of AMD enthusiasts but I have a sneaking suspicion that these crashes are perpetuated by AMD parts. I've always had Intel/Nvidia systems in the past and decided to give AMD a try with my current rig and it has given me nothing but regrets.
I'll list my build below, in case someone much smarter than me can see something wonky about it.
AMD Ryzen 7 5800X Vermeer 3.8GHz 8-core AM4 Processor
MasterLiquid ML240L V2 240mm water cooling
MSI x570S MAG Tomahawk Max WiFi AMD AM4 ATX motherboard
Corsair Vengeance Pro 32GB (2x16) DDR4-3200 PC4-25800 CL 16 Dual Channel memory
MSI AMD Radeon RX 6800 XT Gaming X Triple fan 16GB GDDR6 PCIe 4.0 graphics card
Samsung 980 SSD 1TB M.2 NVMe Interface PCIe 3.0 x4 solid state drive
PowerSpec 850W 80 Plus Gold ATX modular power supply
Lian Li Lancool II Mesh Type C ATX mid-tower case
Microsoft Windows 11 Home
I have three systems in my home, all running BG3 for family members and none of them have an issue so this is not an "AMD" issue. This could be background software related issues.
For owner of AMD GPU cards, I have heard that updating the GPU BIOS can help. Never tried it myself though, and it doesn't seem to be officially supported by the manufacturers. Feels like a bit of high-risk procedure.
NEVER update a GPU BIOS unless directed to do it by the GPU tech support team.