Currently playing Half-Orc Champion as Durge.
Having started many instances and wanting to try something different, I let Shadowheart kill Lae'zel in camp, however, Lae'zel is about the only origin character who approves of your reckless killing, Shadowheart will tolerate it, but the rest leave and I took Karlac's head. I have 2 hirelings (Ranger and Barb) and Shadowheart. Having fun with it.
As far as which class to play, I'd say it doesn't much matter as the game gives everything you need to succeed with any class - just play what you like.
