2. Permadeath, if a character dies, they're dead
3. No revivify scrolls, no withers bringing anyone back,
Thats just one rule, not two. Also, a stupid one. Resurrection is an established part of D&D.
4. One initial respec for companions only,
So ?
Since respec is a PITA thats probably what most people will do anyway.
6. No fast travel unless standing in front of ancient sigil (clicking on it),
7. May only go to camp if standing in front of ancient sigil (clicking on it),
That just wastes time.
8. No using "send to camp" unless already in camp,
That means you'll run out of storage space very quickly and cannot collect heavy items at all.