i think vampires in DnD have more dehumanising issues than the ascended Vampire, which is pretty much a one of a kind in this game. Raphael suggests that the ascended vampire has human lusts and emotions in a way that a normal vampire doesn't. Cazador up to the point of ascension is just a normal although old and strong vampire and I wouldn't want Astarion to turn into him, he has no feelings whatsoever.
