Same thing, I'm stuck in the Mountain Pass. Loads to 33% after the Gith encounter and then CTD when going back to Act 1. I can go to the Shadowlands and continue, but when I try to go back to Act 1 from there it still crashs.

So far both of my playthroughs (and basically my whole experience with the game) have been totally ruined. First because of bugged/missing Minthara content, that no Patch ever fixed for my savegame. And now this gamebreaking bug. I wanted to take the Underdark route this time...