Larian has shown that they hate D&D and all its restrictions and only made BG3 for name recognition.
So why would they make another D&D game and why should we want them to?
I don't feel this strongly about it, though I do think it's obvious they aren't the biggest fans of 5e (at least) and prefer working with their own settings, rather than established ones like the Forgotten Realms.
Either way, I admittedly don't want Larian to make any more D&D games. Between DOS2 and now BG3, it's obvious they struggle with telling a fully consistent story at the best of times, and especially flop hard in Act 3 both writing-wise and performance-wise. Gameplay can sometimes be fun, but even then, there are a ton of rather irritating "Larianisms" which end up becoming death by a thousand cuts for me. Individually annoying but ignorable, yet they build up so much and are so often that it all becomes just a mess for me by the end.
I'd rather BG4 be given to a company that, while not perfect nor tend to release non-buggy games from the offset, seem to actually draw from and respect cRPG roots enough to make some of the most old-school feeling modernized cRPGs I've played to date: Owlcat Studios.
Obsidian-- or whatever they call themselves now, essentially the Pillars of Eternity team --would also be a good choice.
Larian does what they do relatively well, but they seem to (mostly) work best when on their own IP. I'd prefer if WotC gave D&D rights to other companies, if they want to make cRPGs. If they want more NWN2-style "visual" cRPGs, maybe hit up the Solasta devs. Solasta's rough around the edges, but they clearly also love ttrpgs and I think could really make a stand-out game if given enough time and funds for it.