Using or not using the tadpole is also a story choice which the story reacts to, as has been pointed out already.

Proof;
[Linked Image from i.imgur.com]

There are numerous other situations where the story keeps reacting to tadpole usage as well, such as companions and their reactions. The consequences regarding the tadpole is mostly tied to the giga-tadpole as soon as the player gets into ACT 3, at which point there is no more playing around the bush if the player chooses to consume it, which comes with immediate consequences and opportunities.

Whether they're meaningful or not, subjective opinion that is entirely irrelevant. It's a choice which the story reacts to, therefore not an exclusively gameplay only choice.