This bug started happening to me in Wyrms Crossing, act 3. Moved on to the lower city since but it's always present now and the game has become really broken and unplayable. Game is fully updated. It's my second playthrough as Durge, 84 hours in, first one was Tav and got through it without any performance issues, just a few minor glitches and a crash or two for 135 hours.
Here's a clip of several i took demonstrating the problem:
