I created a forum account specifically to add my voice here, as I have had the same issue with saves disappearing. This is not a matter of a few broken quest flags; saving is a core feature of functional SOFTWARE, let alone a GAME. I'm sorry Larian team, but it's your responsibility to find and address the "weird edge cases" , as one of your devs put it, that affect basic functionality. Refund requested and hopefully soon to be approved.