Same, I just reached this point 2 days ago on my second playthough and was so put off by the music. It doesn't fit the mood at all, it's too lighthearted and triumphant when Astarion is having such a cathartic moment, breaking down on the floor after violently stabbing Cazador to death. There is too much whiplash going from dark to hopeful so suddenly and then back to eery ambiance when you have to decide the fate of the spawn. The music is also too loud and overshadows characters speaking.

And what is especially jarring, it also plays in the scene where Astarion has to kill Cazador when you refuse to help him with the ritual (not persuade him out of it, just straight up refuse) and after this cheerful music ends he tells you he hopes you die screaming and leaves the party XD

It surprised me that so few people have been talking about this change so far, when supposedly it has been out for a while.