Shadowheart - Light Domain Cleric

Even if you stick with Shar, if you know which deity is truly granting her powers, then Light makes the most sense.

Lae'zel - Eldritch Knight Fighter or Way of the Four Elements Monk

Githyanki all seem to have a mix of martial and magic. Would make sense for Lae'zel to follow suit.

Karlach - Berzerker Barbarian or Oath of Devotion Paladin

Karlach is a passionate gal. The flames surrounding her when you first meet her and the boost from giving her a Soul Coin are suggestive of a Barbarian Rage. Though it can be possible to justify Oath of Devotion given her ideologies, also the fact that when she decided to turn her life around she became a bodyguard to someone she ended up trusting a lot. Then spent a lot of time killing fiends in Avernus after her betrayal and subsequent servitude to Zariel.

Gale - Conjuration Wizard

Gale is a Wizard through and through. As for school, he seems to have a penchant for conjury, what with him conjuring up images of Mystra or automated copies of himself to deliver messages.

Wyll - The Fiend Warlock and College of Swords Bard

Warlock is obvious given its prominence in his story. But before he got his pact, I could see him be a Swords Bard - The dancing he did and the martial training he received and his preference for a single rapier nudge me towards Swords Bard.

Astarion - Arcane Trickster Rogue

It doesn't come across like he'd have been looking to fight head on prior to becoming a vampire thrall (Also, given how he became one after being beaten up by thugs suggests he didn't have spectacularly amazing fighting capabilities). He seems the sort that would have messed around with people with Arcane Trickster spells (Which would have come naturally to him being a High Elf) in fact, it seems somewhat likely that the reason thugs wanted to beat him up was because he messed around with them too much

Minthara - Gloom Stalker Ranger

I'm no expert on Minthara, since most of my interactions with her involve stabbing her in the face. But what I gather from her is that she's a Drow. She doesn't seem like she's spent her whole life on the surface. So Gloom Stalker might have been how she lived before the Absolute came along and I guess caused her to become Oath of Vengeance Paladin? Honestly, I don't really know.

Halsin - Circle of the Land Druid

While he's fond of his forms and notably his Bear form (Which players can only use as Moon), he seems to be devoted to the land with his idolizing of Silvanus and his connection to Thaniel. He mentions about communing with the lands in regards to him not physically going to places in lieu of his communion.

Jahera & Minsc I've had too little interaction with to get any sense of their class.