I just experienced something like this myself tonight, whether or not its related to mods, I cannot say. I finished the Creche and fast traveled the Emerald Grove Environs waypoint with the intent of getting the forced long rest and starting the Voss conversation. After finishing that, the game was then crashing straight to desktop when I went to rest. Being that I was in an "end of day" state, the only thing I could do was rest which was...crashing the game.
I tried a ton of random things in an attempt to fix it, and since this was an honor mode game there was only one save present so I couldn't roll back, and nothing was seemingly working. I found that dismissing all my companions and resting got past the crash and I could continue as normal.
I don't know if this was a mod causing it, but some light research determined that this particular spot in act 1 has been very problematic with crashes so the root cause is a toss up.
Its always difficult to determine if a mod is causing an issue, or if its just wet spaghetti code.