Most magic items end up as ballast in my backpack. Turns in combat are so precious that I want to use only the most effective items, which means most of the stuff goes unused the entire game.
I think a real challenge would be to use only the odd items sold by Mattis - ring of infinite wishes of course, holy hand soap, spoon of saltiness, etc. I wonder if there is any synergy obtained by equipping all of them? Zero to the fourth power!