Patch 7 is around the corner and it will fix a lot of stuff and give some companions some more to do (poor Wyll hopefully will be allowed to make his own decisions). If you contemplating doing a plythrough, I would wait the few weeks and start with that patch-
As Crimsonrider said, Minthara is pretty bugged and I had her bugging out so heavily last time in act 3, that I just left her in camp after a while. It seems to be better this time though (I play good and recruited her by knocking her out, which is a thing now)
