During the Act 1 encounter with the tieflings and captive Lae'zel, I found an Act 2 repercussion I hadn't expected.
I told the tieflings to shoot down the cage. Lae'zel was killed and the game moved on.
Then in Act 2, I made the mistake of blundering into the Githyanki ambush near the army encampment.
Normally, I would have the Qua'nith Psionic Detector in pocket. However, Lae'zel's death meant Kith'rak Voss doesn't show up at camp to give you the detector.
Thus, there was no warning and the difficult encounter nearly turned into a Total Party Kill. If I hadn't saved the Scroll of True Resurrection Gale's mephit friend gave me after the Wizard of Waterdeep's first death, Shadowheart would have been revived with 1 HP and likely killed immediately before she could heal Tav. They were the only two party members alive, whereas there were still 3 relatively healthy Gith out for blood. It made for an exciting encounter, but I'm a grognard who is too old for this sh*t.
In summary, if you kill Lae'zel, be ready for this eventuality. Or, if you skipped the spoiler, enjoy!