The most obvious sign that Larian planned for negative consequences for tadpole overuse was that Nere could mind control you when you used the tadpole X number of times.
Larian also kept marketing the tadpole as something that has negative consequences even a few days before release, way after they had switched to them being consequence free superpowers.
Hmmm, I wasn’t aware in Nere thing (honestly, I didn’t play around with tadpole powers much in general). On face of it, I am still not convinced it would lead to a overwhelmingly negative narrative outcome (I am not discounting such possibility though!), but it a is a shame if 1.0 doesn’t have such pushback moments. Personally, what interests me most in it is a negative feedback loop it would provide -yes, you gain powerful abilities and easy dialogue checks as you use tadpoles, but every once in a while the game tosses an extra challenge for you to compensate.
Still underlying problem which could potentially change (allowing a worm to eat your brain just sounds like a bad idea) still IMO exists in 1.0. Removing pushback to using tadpole powers have no impact on me as:
1) game is easy enough to break that I don’t need those powers
2) it just sounds like an awful idea for any character, unless that individual is into getting his brain eaten by worms.